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Description / Abstract
The oncoprotein E7 coded for by the human papillomavirus (HPV) is known to degrade the tumor suppressor retinoblastoma protein (pRb). Transient transfections of a plasmid coding for the E7 protein were not effective at visualizing degradation of pRb. Although transient transfection would be efficient in visualizing pRb degradation, the lack of success makes more reliable methods, such as the use of retroviruses, necessary.
Arete: The PLNU Honors Journal
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KeywordsHPV, virus, cancer, oncogene, Arete: The PLNU Honors Journal
Degree AwardedB.S. in Biology
Awarding InstitutionPoint Loma Nazarene University
Committee MembersAriane Jansma
Supervisor or ChairMike Dorrell
Peer Reviewed?No
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PLNU Undergraduate Honors Projects 2016-2020
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